How to Use Hyaluronic Acid Serum for Plumper-Looking Skin

Hyaluronic acid works best when it is layered correctly. Learn when to apply it, what to pair it with, and what to expect.

By Elena Vale Cosmetic chemist, MSc Last updated June 4, 2026

Hyaluronic acid is a humectant, which means it helps bind water so skin looks plumper and more comfortable. Apply it after cleansing and before moisturizer.

Best application

Use 2-3 drops on lightly damp skin, then seal with a cream. If skin feels tight after use, the routine may need a richer moisturizer on top.